This site is being deprecated.
Please see the official X‑Plane Support page for help.
I don't know about the Noble Flight Sim hardware specifically, but you can "pop out" the GPS windows to use on a secondary monitor. The biggest barrier is that the GPS sims don't provide a native way to hide the onscreen bezel and controls to display just the screen. You can, however, "hack" X-Plane to prevent it from displaying the bezels by doing something like this.
This site is no longer being actively maintained.