I did recreate the flight again with all add on scenery removed. All librarys removed and plugin autogate disabled. I left CustomSBDatarefs004, FJCC_FMC, XPLM.framework and XPWidgets.framework enabled because one was part of the aircraft FMC. The others I think were part of X-Plane 11. As I was descending and getting near final, I had another look at simbrief in my browser to make sure the wind and runway were the same as before. The wind and runway had changed at the last moment to opposite direction. PANC 33 instead of PANC 15 but in X-Plane 11 it was still at a direction more in line with 15. I suppose the weather update intervals could have something to do with it. I never forced an update this time. I just changed the approach route in the x737fmc because according to simbrief the wind speed was 0kts anyway and there was no ILS for the opposite direction of runway, that I could see in the arrivals page of the fmc. I'm not sure if the inconsistant wind directions was because of not opening weather settings and causing a weather update or even if I had it would not have synchronized with simbrief as with the last time I tried to do that.