I'm not from Laminar Research, just a fellow simmer in the UK and have the following questions:-
1. With regard to the new replacement hard drive, do you have any other software issues with the operating system and/or 3rd party applications in terms of 'permissions', or does the problem only occur with X-Plane 11?
2. Do you have any antivirus software on your PC that could be blocking use of X-Plane 11?
3. Presumably the new hard drive has been properly formatted and has enough capacity to install X-Plane 11?