I am not familiar with the ERJ-195LR since it is a payware aircraft and not part of the default X-Plane aircraft line up. Do you see this same issue with any of the default aircraft? Was it working at first but has now stopped working?
My first suggestion would be to contact the artist or the place you purchased it through for support.
It's possible there could be differences between the 2D and 3D panels. They have to be designed separately in Plane Maker. It's also possible that certain knobs, switches, etc were not wired up behind the scenes to be manipulable.