Hi, I get the same problem, just after 4 hours of flight and it goes to about 1 fps (but I also don't start on 50 a lot of the time). However inconvenient, and its not really a fix, but the only thing I've found to solve this, and still stay in flight is to reload the current aircraft from one of the drop down menus on the top left of the screen. Sadly you will have to restart your engines and reload a flight plan, along with other small configurations, however it does mean you don't need to restart the flight. Other than that I cant find a fix, sorry.